Polyethylene glycol derivant herders for oil spill mitigation matthew carlin, changhyun choi, monica cuerno, kurt le, amanda massingill, andrew nguyen, omar shafi, joseph yoon, eric zhang, dr. Surfactant replacement therapy has been the mainstay of treatment for preterm infants with respiratory distress syndrome for more than twenty years. Restoring pulmonary surfactant membranes and films at the. The negative charge of bile acids seems to assist the presentation of the phospholipid substrate to the catalytic site.
Ruckenstein department of chemical engineering, state university of new york at buffalo, amherst, new york 14260 received may 17, 1991. Surfactant should be delivered through an inline catheter with the tip located at the mid trachea level. Pdf pulmonary surfactants and their role in pathophysiology of. Emulsifiers, wetting agents, foaming agents, collecting agents there are a vast number of names for surfactants depending on the areas in which they are used. Nanoparticle interaction with model lung surfactant monolayers. Etrects of surfactant and polymer structure, ph, and their synergistic effects on the evolution and properties of the adsorbed layer are discussed. Without surfactants, soaps wouldnt mix with the water, but would just roll off the water, making the cleaning process much more difficult. Ppt introduction to surfactants powerpoint presentation. Pdf surfactant is an agent that decreases the surface tension between two media.
Kindle, acrobat pdf and the app will open in their default web browser, ready. Presentations ppt, key, pdf logging in or signing up. Polyethylene glycol derivant herders for oil spill. In the first case study, the choice of surfactant in relation to solubility and physical stability of the drug substance is shown. A free powerpoint ppt presentation displayed as a flash slide show on id. A a hydrophobic group, such as a hydrocarbon chain, that has no affinity for aqueous solvents b a. The surface active agents which do not disassociate into ions in aqueous solutions are referred as nonionic surfactants. The thesis deals with the synthesis and characterization of surfactants derived from natural products. The result is a decrease in the average distance between the micelles and hence an increase in intermicellar repulsion. Surfactant classification the hydrophilic part is often an ionic group. Tcholakova department of chemical engineering, faculty of chemistry, sofia university, sofia, bulgaria lecture at cost p21 training school physics of droplets. In recent years, the growing interest in noninvasive ventilation has led to novel approaches of administration.
The method can be straightforwardly extended to threedimensions and to soluble surfactants. Surfactantchemistry virginia department of forestry. We use cookies to offer you a better experience, personalize content, tailor advertising, provide social media features, and better understand the use of our services. Liposome dispersion preparation appropriate amount of eyl in chloroform. Application of surfactants interfacial chemistry measuring methods for the research and development of surfactants and their technical use. Surfactant is produced exclusively by alveolar type ii epithelial cells and stored in specialized organelles called lamellar bodies.
Conventional surfactant molecules single chained amphiphile are composed of a long hydrophobic hydrocarbon tail with an ionic or polar hydrophilic head. Gerrard marangonic a saskatchewan research council, 15 innovation blvd. Theyll give your presentations a professional, memorable appearance the kind of sophisticated look that todays audiences expect. Anionic surfactants, which relatively are less expensive, are.
Worlds best powerpoint templates crystalgraphics offers more powerpoint templates than anyone else in the world, with over 4 million to choose from. These are preferred over the ionic surfactants which are usually insoluble in hard water and considered to be poor cleaners. Find powerpoint presentations and slides using the power of, find free presentations research about neonatal surfactant ppt. Surfactant dysfunction is well described in acute lung injury. Surfactants added to cleaning agents, like detergent, allow the detergent to mix into water, helping cleaning agents remove dirt from the surface being cleaned. Ppt micelles powerpoint presentation free to download. A molecular or ion that possesses this type of structure is termed amphipathic amphiphilic. Surfactants form a unique class of chemical compounds. At equilibrium condition the vesiclesurfactant mixtures were left overnight at room temperature. The nonionic surfactants do not form ions in aqueous solution.
Surfactants exhibit a variety of biological effects by themselves and additional effects through modification of the activity of other substances present in the system. A number of surfactants was synthesized from sugars and natural hydrophobic. Because the surfactant actually available at the units is the bovine lipid extract surfactant and the dose should be 5 mlkg 5 mg phospholipidskg divided into one or a maximum of two aliquots. Large droplets dry more slowly than the thin sheets of solution formed by surfactants. A a hydrophobic group, such as a hydrocarbon chain, that has no affinity for aqueous solvents b a hydrophilic group that has an affinity for water. View and download powerpoint presentations on neonatal surfactant ppt. Balance, hlb, appears as a standard section in just about any presentation or course. With regard to the occurrence of related colloidal systems in the petroleum industry, three recent books table 1. Surfactants classification, features and applications surfactants classification, features and applications n. The word surfactant is a blend of surfaceactive agent schematic diagram of a micelle the lipophilic tails of the surfactant ions remain inside the oil because they interact more strongly with oil than with water.
Introduction the lungs of preterm infants lack adequate pulmonary surfactant, a constituent of the air liquid interface, that normally lines the alveolar surfaces and terminal airways. Lecture about surfactants, their properties and classification. Adsorption of surfactants and polymers at the solidliquid interface is a key phenomena in many important processes such as. A level set method for interfacial flows with surfactant jianjun xu zhilin liy john lowengrub z hongkai zhao x abstract a levelset method for the simulation of uid interfaces with insoluble surfactant is presented in twodimensions.
Winner of the standing ovation award for best powerpoint templates from presentations magazine. Virginia department of forestry research report 129 page 3 of 7 6. Surfactant structure all surfactants are characterized by having two regions in their molecular structure. Sulfonic acid salts, alcohol sulfates, alkyl benzene sulfonates phosphoric acid esters, carboxylic acid salts, non toxic as detergents in petroleum oil recovery operation, as in contaminant hydrogeology remediation. Pulmonary surfactants and their role in pathophysiology of. Another beneficial effect of surface tension in water is increased drying time. The nonionic surfactants are less sensitive for electrolytes. Synthesis and characterization of surfactants based on natural. For the most part, surfactant is administered intratracheally, followed by mechanical ventilation. The term surfactant is derived from the term surface active agent and is defined as a substance which at low concentration has the property of absorbing onto the surfaces or interfaces of a system and altering the surface or interfacial energies of those surfaces or interfaces.
Nonionic surfactants have best applications in industries in form of cleaning agents or detergents. Rds is due to surfactant deficiency, which increases the surface tension at the airliquid interface of the terminal respiratory units. Industrial applications of surfactants north american forecast to 2010 is cahas sixth comprehensive multiclient study of industrial surfactants in north america. Mechanistic studies on surfactantinduced membrane permeability enhancement. Surfactant definition surface active agent substance which. It has been divided into two parts, the first dealing with basic chemistry of silicones, and the second dealing with silicone based surfactants. Biological implications of surfactants introduction. The area a occupied by a surfactant molecule at the solutionair interface can be calculated from a 1n a 23. Dans le groupe ncpap, intubation sur les criteres suivants.
We report here, for the first time, the interaction of polyorganosiloxane. One of the most important functions of the lung surfactant monolayer is to form the first line of defence against inhaled aerosols such as nanoparticles nps, which remains largely unexplored. Nagarajan department of chemical engineering, the pennsylvania state university, university park, pennsylvania 16802 e. Surfactant therapy an overview sciencedirect topics. The polar heads of the surfactant molecules coating the micelle interact more strongly with water, so they form a hydrophilic outer layer that forms a barrier between micelles. For a surfactant to permeabilize and acutely damage the intestinal wall, it must exhibit a surface pressure of greater than 25 dynescm. Lecture surfactants free download as powerpoint presentation. Introduction to surfactants why does surfactant work. Surfactants classification, features and applications. It is designed to provide specific market intelligence to support surfactant sales and planning. Chapter 7 spectroscopic characterization of surfactant.
267 1422 965 899 758 1216 375 350 216 1339 1343 1170 1435 155 537 207 1340 601 549 322 533 628 1251 439 343 1267 187 581 160 1276 1228 102 303 542 648 2 924